A rare opportunity to own one of Healdsburg's most prized real estate assets. Built in 1901, 110-116 Matheson Street known as the historic Kruse Building is ideally located in the heart of downtown, just steps from the iconic Healdsburg Plaza. This premier 11,361-square-foot property is anchored by four well-established tenants that embody the charm and vitality of the area. At its core is the Healdsburg Inn on the Plaza, a classic 12-room bed and breakfast operated by the renowned Four Sisters Inn, known for its elevated hospitality and timeless appeal. Complementing the inn are two stylish boutiques, Rete and Ereloom, and the beloved artisan ice cream and pie shop, Noble Folk. The Kruse Building was honored with a Commercial Restoration Award in 1996 for its thoughtful preservation and architectural integrity. In 2005, it underwent a substantial renovation that enhanced both its aesthetic and structural qualities including a seismic retrofit while maintaining its historic character. This is a truly an exceptional opportunity to own a piece of Healdsburg's heritage, in a location surrounded by world-class restaurants, renowned tasting rooms, and the energy of one of Sonoma County's most celebrated destinations.